Antimicrobial evaluation of trisubstituted 2-piperazinyl thiazoles
نویسندگان
چکیده
منابع مشابه
Synthesis and antimicrobial evaluation of certain novel thiazoles.
PURPOSE This article makes an attempt to synthesize certain compounds containing thiazole and imidazole moieties and screen for the antimicrobial properties. METHODS The novel compounds synthesized were characterized by elemental analysis, IR and (1)HNMR spectral data. The antimicrobial activity of novel compounds was evaluated by cup plate method. RESULTS The compound p-t showed more antib...
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Ten 2-substituted 4-thiazolecarboxaldehyde hydrazones bearing 5-nitro-2-furyl, 5-nitro-2-thiazolyl, and 1-methyl-5-nitro-2-imidazolyl functions have been prepared and screened for activity against Trypanosoma cruzi infections in mice. The results permitted the ranking of these substituents in decreasing order of activity: 1-methyl-5-nitro-2-imidazolyl greater than 5-nitro-2-furyl greater than 5...
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ژورنال
عنوان ژورنال: ACTA Pharmaceutica Sciencia
سال: 2019
ISSN: 2636-8552
DOI: 10.23893/1307-2080.aps.05707